External API/backend integrations with Refine

I'm considering using Refine to build a CRUD webapp, but the app would also need to integrate with external APIs such as the Gmail API to perform two key functionalities:
  • Sending emails from within the app
  • Adding new data to an app whenever a certain GMail inbox receives an email
How feasible is this using Refine? If I have to step outside of Refine's framework to manually implement this functionality, how hard is it to step outside of Refine?

Thanks!
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